Share your allergies and medical history with your doctor.
Include any and all allergies (especially to decongestants like pseudoephedrine, amphetamines, or appetite suppressants).
Include your medical history, especially if you have or have ever had diabetes, high blood pressure, glaucoma, personal or familial substance abuse, heart disease, mental or mood problems (depression, anxiety, suicidal thoughts), pulmonary hypertension, stroke, hyperthyroidism, kidney disease, or seizures.
Be aware of (and follow) any restrictions.
Alcohol and marijuana can negatively interact with phentermine, causing severe drowsiness or dizziness.
Do not operate heavy machinery or drive until you are aware of how phentermine affects you.
Be extra vigilant when monitoring your health.
If you have diabetes, check your blood sugar more often and share the results with your doctor in case any adjustments are needed.
Phentermine can negatively affect the health of your kidneys. If you are older or have kidney problems, make sure their doctor is closely monitoring the health of your kidneys.
Note that dissolvable phentermine contains aspartame, so if you have any condition that requires you to limit or avoid aspartame, see your doctor about changing the method of ingestion.
Consider any future physical or medical events.
Women who are pregnant (or plan to be soon) or breastfeeding should not take phentermine. Tell your doctor if you plan to get pregnant or suspect you may already be pregnant.
Tell your dentist and other doctors that you take phentermine prior to having any invasive procedures or surgeries.
Be aware of any drug interactions and associated risks.
Taking certain drugs with (or within 2 weeks of) phentermine can cause increased side effects, a dangerous increase in blood pressure, and abnormal heart rhythm.
Referring to this list should not take the place of discussing drug interactions with your doctor.
These drugs may cause more intense side effects:
* Insulin and oral diabetes medications:
* Nateglinide
* Pioglitazone
* Repaglinide
* Rosiglitazone
* Metformin
* Glimepiride
* Glipizide
* Sitagliptin
* Saxagliptin
* Linagliptin
* Exenatide
* Liraglutide
* High blood pressure and antipsychotic medication:
* Reserpine
Do not take these drugs while taking phentermine:
* Monoamine oxidase inhibitors (MAOIs):
* Isocarboxazid (Marplan)
* Phenelzine (Nardil)
* Rasagiline (Azilect)
* Selegiline (Emsam, Zelapar, Eldepryl)
* Tranylcypromine (Parnate)
* Serotonin reuptake inhibitors (SSRIs):
* Fluoxetine (Prozac, Sarafem)
* Sertraline (Zoloft)
* Fluvoxamine (Luvox, Luvox CR)
* Paroxetine (Paxil, Pexeva, Brisdelle)
* Citalopram (Celexa)
* Escitalopram (Lexapro)
* Nefazodone (Serzone, Dutonin, Nefadar)
* Other weight loss drugs:
* Amphetamine (Adderall, Ritalin, Concerta, Strattera, Focalin, ProCentra, Dyanavel XR, Evekeo)
* Benzphetamine (Regimex)
* Dextroamphetamine (ProCentra, Dexedrine, Spansule, Zenzedi)
* Diethylpropion (Tenuate, Tenuate Dospan)
* Phendimetrazine (Adipost, Anorex-SR, Appecon, Bontril PDM, Bontril Slow Release, Melfiat, Obezine, Phendiet, Plegine, Prelu-2, Statobex)
* Other (and over-the-counter) drugs:
* Amantadine (type-A flu medication, also used for some cases of Parkinson’s)
* Caffeine pills
* Chlophedianol (cough medicines)
* Asthma, allergy, and cold medicines
* Recreational drugs:
* Synthetic Cannabinoids
* Cocaine
