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Pet mice can be cute companions, but their small size makes them susceptible to injuries from falls, attacks by larger pets, and other trauma. It’s always the safest bet to contact your vet whenever you suspect an injury to your mouse. Minor wounds can often be treated at home, but the risk of infection or injury aggravation is higher without your vet’s involvement.

Method 1
Method 1 of 3:

Taking Action When You See an Injury

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  1. Infections can spread rapidly due to a mouse’s small size, so it’s better to be safe than sorry anytime you see a cut or wound on your mouse. Always call the vet right away if you suspect potential internal injuries (e.g., the mouse fell from a distance or was stepped on) or broken bones.
    • As prey animals that are hunted by others, mice are good at both concealing themselves and their injuries. So, whether you can see or just suspect an injury, assume it is more serious than the mouse makes it appear.
  2. If you call your vet and they give you the “all clear” on a minor flesh wound, your main job will likely be to observe it and keep it relatively clean. If instructed to do so, rinse the wound with clean water (from a dropper or bulb syringe) and wipe it with a cotton swab or cotton ball. Apply an antibacterial spray or ointment if directed by your vet.
    • Minor wounds to a mouse’s body usually don’t bleed heavily and heal fairly quickly.
    • To reduce the risk of infection, you may be instructed to clean the mouse’s enclosure more carefully and frequently (e.g., daily instead of weekly). Or, you may even be advised to put the mouse in a separate, extra clean cage, away from its typical companions.
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  3. Injuries to the legs, nails, tail, and face tend to bleed more heavily than those to the body. Once you identify the source of a bleeding wound, hold a clean cloth to the wound for 2 minutes. If it’s still bleeding, either reapply pressure for 2 more minutes or apply flour or cornstarch to the bleeding wound. [1]
    • For a wound that is bleeding profusely, try to stanch this bleeding before you call your vet.
  4. Whether you end up visiting the vet or just calling them for guidance, you may be advised to give your mouse pain medication for an injury. In many cases, vets will recommend either ibuprofen or acetaminophen (Tylenol) for pain management. Follow their guidance on dosing and administering the medication. [2]
    • Typically, pet rodents will be given 15-60 mg of ibuprofen per pound of body weight, every 6-12 hours. Ibuprofen can affect blood clotting, though, so your doctor may recommend 90-140 mg/lb of acetaminophen every 6-12 hours instead.
    • You may be advised to give them liquid children’s ibuprofen or acetaminophen with a medication syringe, or to crush up a portion of an adult tablet to mix into yogurt, baby food, or mashed avocado.
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Preparing and Watching for Injuries

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  1. Instead of scrambling around looking for supplies and your vet’s number after an injury to your mouse, spend a little time organizing what you’ll need in one place. Put everything in a shoebox, small plastic tote, or—best of all—the small pet carrier you use when taking your mouse to the vet. Include items like: [3]
    • an index card with your vet’s contact info and any relevant medical information for your mouse
    • 1-2 clean towels
    • rubbing alcohol to sterilize tools
    • antibiotic ointment
    • latex gloves to limit bacteria transmission
    • an eye dropper or bulb syringe for rinsing wounds
    • cotton swabs and cotton balls for cleaning wounds
    • fingernail scissors or clippers for trimming hair from wounds or broken nails
    • flour or cornstarch to help stanch bleeding
  2. Gaping wounds and broken limbs can be easy to spot, but your mouse may be able to conceal signs of many injuries. Watch out for physical or behavioral changes like:
    • hiding more than usual
    • not eating and/or drinking
    • limping or not using a limb
    • unusual bumps or lumps on the body
    • labored or loud breathing
    • unexplained weight gain or loss
  3. Each morning, take a few minutes to simply watch your mouse. Look for any unusual behaviors or physical symptoms that might indicate an injury or illness. Check that the mouse has consumed its normal amount of food and water during the night, and that the amount and texture of its droppings are normal.
    • If something appears obviously wrong, contact your vet. If you’re not convinced something is wrong, check regularly over the next few hours and call the vet if your suspicions remain.
  4. Pick the mouse up gently in your cupped hands, then use your thumbs and fingers to lightly feel for any hidden wounds or abnormal bumps on its body. Praise the mouse in a soothing voice as you work.
    • Consider doing this physical exam each week while you are deep cleaning the mouse’s enclosure. That way, you won’t have to disrupt its normal routine twice.
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Method 3
Method 3 of 3:

Preventing Injuries

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  1. Most mice don’t particularly enjoy being picked up or held, so limit how often you do so. When you do pick up a mouse, use one of two methods:
    • Grasp it near the base of its tail—never near the end of the tail—with one hand, and support its body with your other hand as you lift the mouse. You can dislocate the tail or even sever the tip of it by lifting from the end of the tail.
    • Cup your hands around the mouse and lift it. If it tries to climb out, loosely cup your hands closed. After 15-30 seconds, most mice will stop trying to escape and will accept being held in your hands this way.
  2. Mice are skilled escape artists and can squeeze through surprisingly small spaces. For their home, choose either a cage that is made specifically for mice, or an aquarium with a mouse-approved screen lid. If there is a door or gate, make sure it latches securely.
    • A mouse enclosure should be roomy, but not more than about 2 ft (61 cm) high. Mice like to climb, but falling from any more than a small height can cause serious injuries.
  3. Keep cats, dogs, and other potential predator pets outside the room where your mouse lives. Don’t trust the cage alone to keep your mouse safe.
    • All children under about age 8, and children of any age without experience with pet mice, should be supervised closely. They’re more likely to injure a mouse by unintentionally squeezing it, dropping it, or stepping on it.
  4. Mice are social creatures that prefer company, but males kept together will usually end up fighting and possibly injuring each other. It’s best to keep 2 or more females together, or a neutered male with 1 or more females.
    • If you put a male that isn’t neutered in with 1 or more females, expect to have a lot of baby mice to take care of soon after!
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Community Q&A

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  • Question
    My mouse can't walk at all and has labored breathing. What should I do?
    Community Answer
    Make him comfortable in his carrier (a box will do if you don't have a carrier). Place some paper towels in the bottom and rush him to the vet immediately.
  • Question
    One of my 2-year-old mouse's eyes looks inflamed and protruding. What should I do?
    Community Answer
    It sounds like your mouse has either an infection, or has had some kind of trauma to their eye. You need to take it to the vet, as this can be serious.
  • Question
    How do I take care of a mouse that keeps running in circles from stress?
    Community Answer
    Gain its trust. Use a soft voice, slow movements and so on. Start small and work your way up before coming into full contact with it. Don't give him a reason to fear you.
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