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The time has come for you to choose a side. Legion, NCR, Independent, or House. Let's just assume that you're not choosing House. How do you take him out of the picture? Read on to find out how.

  1. Power armor works best.
  2. Make sure it is relatively easy to use, like a mini-gun, rocket launcher, or Gatling laser. Alternatively, you can use a Pulse Gun (your main enemies are robots).
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  3. Preferable options would be Veronica or Lily.
  4. Go inside the Lucky 38.
  5. Go to the room you find Mr. House's monitor.
  6. You should find another room. Find the terminal located on the wall.
  7. Mentally mark its position, then go back to the terminal.
  8. Confirm the order.
  9. Do not worry about the ones behind you.
  10. Do not take off your armor; you will need protection more than agility. Race for the terminal in the other room.
  11. Open the elevator.
  12. House's chamber. You can open the cryo-storage to rid him of access to the sentries, or assassinate him.
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      Tips

      • Bring along some Stimpacks or Doctor's Bags to heal broken limbs (the sentries will fire rockets and gatling lasers).
      • Raise the stats of a particular weapon skill (Guns, Explosives, Energy Weapons, Unarmed, Melee) to be more effective with them.
      • You can raise your Agility under S.P.E.C.I.A.L. at the beginning of the game.
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      Warnings

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