Q&A for How to Unlock The Lost in The Binding of Isaac: Rebirth

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Question

Is it worth unlocking it if you're not going for Real Platinum God?

Community Answer

The items are definitely worth the effort and pain of doing everything as the lost, as they are really strong, helpful, and might as well be OP. It is harder to unlock the lost in Rebirth but in Afterbirth you got 3 more challenges on the completion post-it note. It can be a pain but, like I said, worth it.

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Question

Does picking up the dead cat and dying on one of the early lives affect how the azalea part works in Binding of Isaac?

Community Answer

No, it doesn't. It needs the actual death screen to count for you to restart.

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Question

Will The Lost unlock if I use seeds?

Community Answer

You can use a seed for the first three characters in Rebirth, but not for Azazel.

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Question

Do I need to die entering the room or on the spikes?

Community Answer

You need to die on the spikes.

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Question

Are the input seeds correct?

Community Answer

For rebirth yes, you can unlock the lost by using this method.

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Question

Do I actually need to beat the lamb?

Community Answer

No, but it is faster than the first option, taking about 4 different runs plus the retries to get the right items. Defeating the lamb is part of getting Real Platinum God, but if you're not going for Real Platinum God and you have time, then the first one is OK. None of the characters are unlocked by beating the lamb, so it doesn't really matter.

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Question

Can I do these out of order?

Community Answer

No, you cannot.

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Question

What if I die when trying to get the lost in Binding of Isaac: Rebirth?

Community Answer

If you die, you have to restart the steps. If you are about to die, quickly press escape and exit the game or hold R. If you do this before the death screen pops up, you don't have to restart.

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Question

Does dying in the flooded cave count?

Community Answer

Yes, it does.

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Question

Can I unlock the lost in Rebirth by having the missing poster and dying in the sacrifice room?

Community Answer

If you do this, it will tell you the 4 characters you have to die with and how you're supposed to die, but that is already covered in this wikiHow article, so it isn't necessary.

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Question

Will the rebirth method of unlocking The Lost also work in Afterbirth?

Community Answer

No, the seeds don't work.

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Question

Can I take blue hearts in the fourth level?

Community Answer

Yes, you can. They're called soul hearts.

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Question

How do I restart Binding of Issac?

Community Answer

Press the X on top right or top left.

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Question

Can I unlock the lost in afterbirth the way I do in rebirth?

Community Answer

Afterbirth has a different unlock than rebirth. You need to get the Missing Poster trinket and die in the sacrifice room.

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