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If you have an uncomplicated yeast infection (i.e., an infection with mild to moderate symptoms that does not recur frequently and is not associated with any other medical conditions) and want to treat it with an over-the-counter medication, use Monistat 3. Prefilled applicators are easy to use, but messy. Suppositories are quick to insert. Ovules are like suppositories, but they're less likely to leak out and create a mess as they dissolve. Insert 1 prefilled cream applicator, suppository, or ovule into your vagina every day for 3 days. 90% of women get relief from yeast infection symptoms after completing the recommended course of Monistat treatment. Speak to your healthcare provider if you have an allergic reaction, side effects, or if the yeast infection doesn't clear up.

Part 1
Part 1 of 3:

Choosing a Monistat 3 Product

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  1. The box will come with 3 prefilled applicators that contain medicated cream. Each cream applicator has 200 mg of miconazole nitrate. The package may also have a tube of external anti-itch cream. [1]
    • The prefilled cream applicators are thought to be the messiest of the Monistat 3 options, but they're usually the least expensive.
  2. A package has 3 suppositories that each contain 200 mg of miconazole nitrate. The package will also come with 3 applicators for inserting the suppositories. [2]
    • We'll tell you how to insert the product in the next section.
    • Suppositories often include a tube of anti-itch cream for external application.
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  3. If you'd like to use the Monistat treatment during the day instead of at night, buy the Less Mess ovules. The ovules aren't as messy as the Monistat suppositories. A package has 3 doses of 200 mg of miconazole nitrate. The package might also include 1 tube of anti-itch cream to use externally. [3]
    • The ovules are similar to suppositories, but they aren't as messy since they dissolve more slowly.
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Part 2
Part 2 of 3:

Inserting the Product

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  1. To prevent the spread of disease, wash your hands well with soap and water. Dry your hands thoroughly to make it easier to open the product packaging. [4]
  2. Regardless of whether you choose the cream, suppository, or ovule, you'll need repeat the treatment once per day for 3 days. [5]
    • Only use 1 treatment rather than combining treatments or using multiple treatments.
    • We'll tell you how to use Monistat 3 effectively in the next section.
  3. Take out a prefilled applicator and unscrew the cap. Push the small end of the plunger into the gray hole at the end of the applicator barrel. Insert the applicator into your vagina as far as it can go comfortably. Push the plunger to get the cream into your vagina. [6]
    • Remove and throw away the plunger and applicator.
  4. Separate a suppository wrapper to remove 1 suppository. Set the suppository on the end of 1 applicator and insert it directly into your vagina. Insert it as far as it's comfortable and then pull the applicator back out. Discard the applicator. [7]
    • Try to lie down immediately after inserting the suppository since it will start to leak out as it dissolves.
  5. Push 1 ovule out of the foil packet and set it on the end of 1 applicator. Insert the applicator into your vagina as far as it feels comfortable. Push the end of the applicator toward you so the ovule is released into your vagina.
    • Throw away the applicator once you pull it out.
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Part 3
Part 3 of 3:

Using Monistat 3 Effectively

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  1. Because the treatment will begin to leak out as it dissolves, try to lie down immediately after inserting the cream or suppository. This is why most women use these Monistat treatments right before bed. [8]
    • It's also a good idea to wear pantyliners to protect your underwear from any leakage.
    • The Monistat 3 ovules will dissolve without leaking, so you can use these during the day.
  2. While you can treat a yeast infection during your period, don't insert tampons after you've used Monistat. The tampons can absorb the medication, so use pads instead. [9]
  3. You should avoid using condoms, diaphragms, or cervical caps until you've finished the treatment. The Monistat 3 medication can weaken these forms of birth control, so use an alternative form of birth control until treatment is complete. [10]
    • For example, switch to a hormonal method such as the pill or an intrauterine device (IUD).
  4. You may experience some abdominal cramping, headaches, hives, or skin rash. If these side effects don't go away or become worse, you may have an allergic reaction. [11]
    • Contact your healthcare provider for advice about whether to stop using the Monistat.
  5. Some women notice a brief burning sensation when they start using Monistat 3. If you do, you might want to switch to Monistat 7, which is a lower dose. [12]
    • Keep in mind that you'll need to take the treatment for 7 full days instead of 3 because of the difference in dosing.
  6. You should notice an improvement in symptoms within 3 days, but talk with a doctor if the yeast infection isn't gone after 1 week. Your healthcare provider may find that the infection wasn't actually a yeast infection and prescribe a different treatment. [13]
    • Talk with your healthcare provider if the same symptoms come back within 2 months of treating it. This can mean that something else is causing your infections.
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      Warnings

      • If your yeast infection is associated with an underlying chronic medical condition (such as diabetes) or if you receive regular corticosteroid treatments, your yeast infection will probably not respond well to short-term treatments like Monistat 3. Talk to your healthcare provider about alternative options.
      • Speak to your healthcare provider to ensure you do have a yeast infection before using an over-the-counter treatment.
      • If you're pregnant or nursing, avoid using Monistat 3. [14] Instead, the Centers for Disease Control and Prevention recommends using a 7-day topical treatment.
      • Talk to your healthcare provider if you have 4 or more yeast infections in a year. [15]
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      Tips

      • If you have any male sexual partners who may have been exposed to your yeast infection, they probably will not need to receive treatment.
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      Things You'll Need

      • Monistat 3 ovule, suppository, or prefilled applicator
      • Soap and water

      About This Article

      Article Summary X

      Monistat 3 is a good option for treating mild yeast infections. However, if your symptoms are more severe or don’t go away with over-the-counter products, see your doctor. Monistat 3 comes in different forms, like pre-filled cream applicators, suppositories, and ovules. To use the cream applicators, take 1 out of the box and unscrew the cap. Push the small end of the plunger into the gray hole at the end of the applicator, then insert the applicator into your vagina as far as it will comfortably go. Push the plunger to release the cream. If you’d rather use a suppository, first, remove it from its wrapper. Then, set the suppository on the end of 1 applicator and insert it directly into your vagina. Pull the applicator back out and discard it. Both suppositories and cream applicators are best used right before bed so the treatment doesn’t leak out right away. It’s also a good idea to wear a pantyliner to protect your underwear from leakage. To learn how to use monistat 3 ovules, read more from our Medical co-author!

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