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In order to determine the correct Frontline Plus dosage, first you will need to establish your dog’s weight. You can either weigh your dog at home, or at the vet’s office. Frontline Plus comes in four different boxes. Weight limits are stated on each box in the lower left hand corner. If your dog weighs more than 132 pounds, or has an in-between weight, then you will need to adjust the dosage accordingly. [1]

Method 1
Method 1 of 2:

Weighing Your Dog

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  1. To determine the correct Frontline Plus dosage, you will need to establish your dog’s weight. To determine your dog’s weight, you will need to weigh yourself first. [2]
    • Take off your shoes, and take keys, cellphones, and other belongings out of your pockets. Then, step on the scale. Wait a few seconds for the scale to stabilize, and record your weight. Step off.
    • Do not hold on to anything while you are on the scale. This will produce an inaccurate reading.
  2. Pick up your dog . While holding your dog, step onto the scale again. After the scale stabilizes, record the total weight. Step off the scale. [3]
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  3. Subtract your weight from the total weight, i.e., the weight of you and your dog together. The resulting number is your dog’s weight. [4]
    • For example, if your weight is 120 pounds and the weight of you plus your dog together is 150 pounds, then subtract 120 from 150. The remaining number, 30, is the weight of your dog.
  4. If you do not have a scale at home, or if your dog is too heavy to pick up, then take your dog to the vet’s office. Your veterinarian will have a scale that can weigh small, medium, and large dogs.
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Method 2
Method 2 of 2:

Buying the Correct Box

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  1. Frontline Plus is a topical medication that is used to prevent and kill fleas and ticks. You will need to re-apply it once a month. Only use Frontline Plus on dogs that are eight weeks of age or older. [5]
  2. Frontline Plus comes in four different boxes that are differentiated by weight. If your dog weighs 22 pounds or less, then buy the 5 to 22 lb. box. The basic 5 to 22 pound box comes with three .67ml applicators. Only use one applicator per application. There are also 6 and 12 pack boxes available. These come with 6 or 12 .67ml applicators. [6]
    • If your dog weighs 23 to 44 pounds, then buy the 23-44 lb. box. The 23-44 lb. box comes with three 1.34ml applicators.
    • If your dog weighs 45 to 88 pounds, then buy the 45-88 lb. box. The 45-88 lb. box comes with three 2.68 applicators.
    • If your dog weighs 89 to 132 pounds, then buy the 89-132 lb. box. The 89-132 lb. box comes with three 4.02ml applicators.
  3. If your dog’s weight is in between two different weight ranges, then use the box with the lower amount. In other words, round down instead of rounding up. It is always better to use less rather than more in order to prevent an overdose. [7]
    • For example, if your dog weighs 22.5 pounds, then use the 5 to 22 lb. box.
  4. If your dog weighs more than 132 pounds, you will need to combine products in order to get the correct dosage. This means you will need to buy more than one box. You will need to buy the 89-132 lb. pound box plus an additional box. The additional box you use depends on how many pounds of your dog's weight exceed the 132 limit. [8]
    • For example, if your dog weighs 152 pounds, then apply a 4.02ml applicator and a .67ml applicator since your dog is only 20 pounds over. However, if your dog is 30 pounds over, i.e., 162 pounds, then use a 1.34ml applicator in addition to the 4.02ml applicator.
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      About This Article

      Article Summary X

      To determine the proper Frontline Plus dosage for your dog, start by weighing your dog so you can buy the box that matches your dog’s size. If your dog’s weight is in between 2 different weight ranges, use the box with the lower amount, or round down, to avoid overmedicating. For example, if your dog weighs 22.5 pounds, use the 5 to 22 pound box. However, if your dog weighs more than 132 pounds, you’ll need to combine products to get the correct dosage. As an example, if your dog weighs 150 pounds, buy the 89 to 132 pound box plus the 5 to 22 pound box. For more tips from our Veterinary co-author, including how to know if your dog is old enough for Frontline Plus, keep reading!

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      • Doug Anton

        Apr 28, 2017

        "I have several doses of Frontline Plus (FLP) for a 22-44 lb. dog. My Cocker Spaniel passed away last year and I now ..." more
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