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Onycholysis is the gradual, painless separation of a fingernail or toenail from its nail bed. The most likely cause is trauma, but other factors could affect it. Visit your doctor to determine the cause of your onycholysis. If an underlying medical condition is to blame, your doctor will help you treat it so that your nails can heal. If injury or prolonged exposure to moisture or chemicals caused your onycholysis, it will likely go away with the proper treatment and preventative measures.

Method 1
Method 1 of 3:

Determining the Cause

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  1. Your doctor should be able to determine the cause of your onycholysis by examining your nails. They may also take a tissue sample from underneath one of your nails to test for fungus or other infections. See your doctor if: [1]
    • One or more of your nails have lifted from the nail bed underneath
    • The border between your nail bed and the white outside of your nail on one or more of your nails is unevenly shaped
    • A large portion of your nail(s) are opaque or discolored
    • One or more of your nails plates are deformed with indentations or bent edges
  2. Some medications can make your nails react to sun exposure, resulting in nails that lift away from their nail beds. Medicines in the psoralen, tetracycline or fluoroquinolone categories are the most notable causes of this reaction. Tell your doctor about any prescription or over-the-counter medications you are taking to rule out this possible cause. [2]
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  3. Tell your doctor if you have been diagnosed with psoriasis in the past, as the majority of psoriasis patients are likely to develop onycholysis at some point. [3] If you have not received this diagnosis, tell your doctor about any skin problems you may have experienced recently. Symptoms of psoriasis can include: [4]
    • Dry, cracked, or bleeding skin
    • Red patches of skin
    • Silvery scale marks on the skin
    • Itchy, burning, or sore skin
  4. Trauma to the nail bed can cause onycholysis gradually and painlessly. [5] Tell your doctor if you have experienced any injuries that may have affected your nails. This may include impact injuries and piercing injuries where the nail was cut or torn.
    • Injuries may range from small incidents like stubbing your toe to more major accidents, such as slamming your finger in a car door.
  5. Exposure to stressors can damage your nails, eventually leading to onycholysis over time. Consider your regular cleaning, grooming, and physical activities to determine what habits might be to blame. These environmental or occupational stressors could include: [6]
    • Prolonged periods in water (e.g. frequent swimming or washing dishes)
    • Regular use of nail polish, artificial nails, or nail polish removers
    • Frequent exposure to chemicals, such as cleaning products
    • Closed toe shoes while walking with uneven pressure from flat feet [7]
    Bianca Maria Piraccini, Nail Disorder Specialist

    While onycholysis itself cannot be cured, identifying and properly managing the underlying cause can allow new, healthy nail growth to occur. Have patience, as it takes time for nails to regenerate. In the interim, gently care for nails by keeping them dry and neatly trimmed. With diligent at-home care and treatment of any medical conditions contributing to nail separation, one can support proper reattachment over time.

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Method 2
Method 2 of 3:

Treating Onycholysis

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  1. Nails that have separated from their nail beds are vulnerable to injury. Use nail clippers or scissors to remove the affected nail as it grows out, or ask your doctor if they can remove the separated part of the nail for you in-office. [8]
    • If you have an infection under your nail, removing it will allow you to apply the medication directly to the site.
  2. Before your nail can grow back, the fungus and bacteria under the nail must be killed. After diagnosing this kind of infection, your doctor will prescribe an oral or topical antifungal medication to treat it. Take or apply the medication exactly as directed until a new, healthy nail begins growing in. [9]
    • Oral medications should be taken for 6-24 weeks depending on the severity and nature of the infection.
    • Topical creams or ointments should be applied daily around the nail bed and are usually slow to produce results.
    • Oral medications are generally more effective than topical ones, but carry additional risks such as potential liver damage.
    • Follow up with your doctor after 6-12 weeks of treatment.
  3. Psoriasis is a common cause of onycholysis that has a number of possible treatments. Discuss treatment options with your doctor to decide which one may be most effective for you. These options may include: [10]
    • Oral medications like methotrexate, cyclosporine, and retinoids
    • Topical treatments like corticosteroids, synthetic vitamin D, anthralin, calcineurin inhibitors, salicylic acid, and topical retinoids
    • Light therapy treatments, such as UVB phototherapy, narrow band UVB phototherapy, and excimer laser therapy
    • Alternative, natural treatments like aloe vera, fish oil, and topical applications of Oregon grape have also been used as effective treatments against psoriasis-linked onycholysis in some studies. [11]
  4. A lack of vitamins and minerals may leave your nails weak and brittle, making it more difficult for them to regrow after onycholysis. Ask your doctor if you should take supplements to help your nails regain strength. Iron in particular may help to strengthen your nails. [12]
    • Biotin, a B vitamin, can also help to improve the condition of your nails.
    • Taking a daily multivitamin will help to guarantee that you get an assortment of vitamins that your body needs for overall health. [13]
    • Your doctor may also suggest dietary changes to increase your intake of certain vitamins and minerals.
  5. To protect your nails from excessive moisture while they are healing, apply a drying substance to them after getting your hands or feet wet. Ask your doctor if they can prescribe a drying agent such as 3% Thymol in alcohol. This kind of liquid drying agent should be applied directly to the nails with a dropper or small brush. [14]
    • These drying agents should be used for 2-3 months while your nails are healing.
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Method 3
Method 3 of 3:

Preventing Onycholysis

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  1. Prevent the growth of bacteria or fungus under your nails by washing them frequently during the day. Lather them with a mild hand soap and rinse them thoroughly. Be sure to dry them thoroughly after they get wet to further prevent fungal infections. [15]
  2. Small shoes will put more pressure on your toenails and make it more likely to cause trauma. Prolonged trauma on your nails is likely to lead to the development of onycholysis.
  3. Wet feet can cause toe fungus, which may result in onycholysis. Wear waterproof shoes or boots if you are walking or exercising in wet conditions. Remove sweaty socks and shoes right after exercising to prevent the growth of bacteria or fungus. [16]
    • Let your shoes air-dry thoroughly if they get wet.
    • If you exercise frequently, consider buying multiple pairs of athletic shoes to avoid wearing wet or damp footwear.
  4. Both prolonged exposure to chemicals and frequent submersion in water can cause onycholysis. Protect your hands by wearing rubber gloves while cleaning the house, washing dishes, or performing similar tasks. Gloves will also protect long nails from injury when performing household chores. [17]
  5. It is easier for moisture and bacteria to build up under long nails, creating a greater risk of onycholysis. To prevent this condition, trim your nails regularly to keep them short and neat. [18] Use clean nail clippers to cut your nails and an emery board to smooth the edges.
    • Shorter nails will also be less prone to injury or trauma.
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      About This Article

      Article Summary X

      If you want to cure your onycholysis, make sure to see your doctor to find out the cause and determine the best treatment options. Since nails separated from their nail beds can lead to further injury, ask your doctor to trim yours, since doing it yourself could cause infection. For onycholysis caused by a fungal infection, use an antifungal medication prescribed by your doctor. Make sure to apply any topical creams around the nail bed daily. To protect your nails from excessive moisture as they heal, apply a drying substance like Thymol in alcohol to them after getting your hands or feet wet. For more advice from our Medical co-author, like how to prevent onycholysis, scroll down.

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